Prep HPLC Column, RP C4, 5um, 100A. 30mm ID x 100mm Length. Cogent Brand. 1 EA. Special Order Item.

Additional Information:

Cogent RP C4™ is a reversed-phase HPLC stationary phase designed for the purification and isolation of hydrophobic and neutral compounds. Manufactured using a four-carbon butyl ligand bonded to ultra-high purity silica and fully double end capped, this stationary phase provides reproducible chromatographic performance and reduced hydrophobic retention compared to C8 and C18 phases. The chemistry is particularly useful for preparative-scale separations where efficient recovery and purification of target compounds are required.

68504-P30-100 is a preparative HPLC column packed with 5 µm RP C4™ particles featuring a 100 Å pore size in a 30 mm ID x 100 mm format. The large internal diameter provides substantial sample loading capacity for purification applications, while the 100 mm length offers an excellent balance between throughput and chromatographic resolution. The 5 µm particles provide lower operating backpressure than smaller particle sizes, making the column well suited for preparative HPLC systems. Typical operating flow rates are approximately 30–60 mL/min depending on mobile phase composition, analyte characteristics, and system capabilities.

This column is particularly useful for the purification of hydrophobic and neutral compounds in pharmaceutical, chemical, and research laboratories. Compared to C8 and C18 phases, the C4 bonded phase generally provides lower retention, which can improve recovery and reduce purification cycle times. The 30 mm ID format provides higher loading capacity than 21.2 mm preparative columns and is well suited for demanding purification workflows. A specialized preparative HPLC system is required for operation.

Key Benefits

  • RP C4™ stationary phase

  • USP L26 equivalent chemistry

  • Butyl (C4) bonded phase

  • Fully double end capped

  • Ultra-high purity silica support

  • Lower retention than C8 phases

  • High sample loading capacity

  • Lower operating backpressure than smaller particles

  • 5 µm particle size

  • Optimized for preparative HPLC

Typical Applications

  • Preparative HPLC

  • Compound purification

  • Fraction collection

  • Pharmaceutical purification

  • Hydrophobic compound purification

  • Neutral compound purification

  • Process development

  • Method development

  • Research and development

  • Laboratory-scale production

Specifications

  • Product Type: Preparative HPLC Column

  • Stationary Phase: RP C4™

  • USP Classification: L26

  • Chromatography Mode: Reversed Phase

  • Bonded Phase: Butyl (C4)

  • Endcapping: Fully Double End Capped

  • Particle Size: 5 µm

  • Pore Size: 100 Å

  • Column Dimensions: 30 mm ID x 100 mm

  • Length: 100 mm

  • Typical Flow Rate: 30–60 mL/min

  • Brand: Cogent

Special Order Item Information

Important Notes

  • Designed for preparative purification of hydrophobic and neutral compounds

  • Provides less retention than C8 stationary phases

  • High loading capacity for preparative-scale applications

  • The 30 mm ID format requires a specialized preparative HPLC system

  • Typical operating flow rates are approximately 30–60 mL/min

  • 5 µm particles provide lower operating backpressure and robust performance

  • Fully double end capped to minimize secondary interactions

  • The 100 mm length provides an excellent balance of throughput and chromatographic resolution

  • Excellent choice for preparative purification and fraction collection

  • This is a Special Order Item


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